李映红，男，汉族，1987年生，四川广安人，九三学社社员，博士，副教授，硕士生导师，重庆邮电大学生物信息学院生物信息学系副主任，重庆市生物信息学会理事， Nucleic Acids Research，Briefings in Bioinformatics，Frontiers in Oncology等期刊审稿人。主要从事：人工智能与药物发现、中医药现代化、单细胞多组学分析 等研究工作。目前主持国家级及省部级科研项目5项，纵向其他项目2项，横向项目2项，以第一作者及通讯作者身份发表SCI论文14篇。

本课题组最新的论文、开源代码及相关数据集，请访问实验室主页：https://lab.lyhbio.com/

论文列表（以第一作者和通讯作者身份发表）：

1. Jielong Mou^#, Yudong Yan^#, Boren Jiang, Fan Yang, Zupeng Pan, Xuanhao Huang, Mingze Bai, Zhijie Han*, Yinghong Li*. LKE-DTA: predicting drug-target binding affinity with large language model representations and knowledge graph embeddings. Molecular Diversity (IF=3.8, 中科院二区). doi: 10.1007/s11030-025-11394-1 (2025)

2. Yinghong Li^#, Fan Yang^#, Zupeng Pan^#, Yudong Yan, Boren Jiang, Xuanhao Huang, Hongyin Wang, Xiang Qin, Su Zeng, Tingting Fu*, Feng Zhu*. VARIDT 4.0: distribution variability of drug transporters. Nucleic Acids Research (IF=13.1, 中科院二区top). doi: 10.1093/nar/gkaf981 (2025)

3. Yinghong Li^{*, #}, Yudong Yan^#, Zhuohao Tong, Yu Wang, Yinqi Yang, Mingze Bai, Dan Pu, Jiazheng Xie, Chuan Liu, Bo Li*, Mingwei Liu, Kunxian Shu*. Efficient fine-tuning of small-parameter large language models for biomedical bilingual multi-task applications. Applied Soft Computing (IF=6.6, 中科院二区top). 175:113084 (2025)

4. Yudong Yan^#, Yinqi Yang^#, Zhuohao Tong, Yu Wang, Fan Yang, Zupeng Pan, Chuan Liu, Mingze Bai, Yongfang Xie, Yuefei Li*, Kunxian Shu*, Yinghong Li*. Adaptive multi-view learning method for enhanced drug repurposing using chemical-induced transcriptional profiles, knowledge graphs, and large language models. Journal of Pharmaceutical Analysis (IF=6.1, 中科院一区). 15(6):101275 (2025)

5. Yinghong Li^#,*, Zhuohao Tong^#, Yinqi Yang, Yu Wang, Lu Wen, Yuke Li, Mingze Bai, Yongfang Xie, Bo Li*, Kunxian Shu*. Lung Cancer Biomarker Database (LCBD): A Comprehensive and Curated Repository of Lung Cancer Biomarkers. BMC Cancer (IF=3.4, 中科院二区). 25: 478 (2025).
   

6. Hongrui Duo^#, Yinghong Li^#, Yang Lan^#, Jingxin Tao, Qingxia Yang, Yingxue Xiao, Jing Sun, Lei Li, Xiner Nie, Xiaoxi Zhang, Guizhao Liang, Mingwei Liu, Youjin Hao, Bo Li. Systematic evaluation with practical guidelines for single-cell and spatially resolved transcriptomics data simulation under multiple scenarios. Genome Biology (IF:12.3, 一区top). 25: 145 (2024). 

7. Yinghong Li^#, *, Yinqi Yang^#, Zhuohao Tong, Yu Wang, Qin Mi, Mingze Bai, Guizhao Liang, Bo Li*, Kunxian Shu*. A Comparative Benchmarking and Evaluation Framework for Heterogeneous Network-Based Drug Repositioning Methods. Briefings in Bioinformatics (IF:9.5, 一区). 25(3):bbae172 (2024).

8. Ding Luo, Zhuohao Tong, Lu Wen, Mingze Bai, Xiaojie Jin, Zerong Liu, Yinghong Li*, Weiwei Xue*. DTNPD: A comprehensive database of drugs and targets for neurological and psychiatric disorders. Computers in Biology and Medicine (IF:7.7, 一区). 175:108536 (2024).

9. Weichen Bo, Dongya Qin, Xin Zheng, Yue Wang, Botian Ding, Yinghong Li*, Guizhao Liang*. Prediction of bitterant and sweetener using structure-taste relationship models based on an artificial neural network. Food Research International(IF:6.475, 一区top). 153:110974 (2022).

10. Ying Hong Li^#, Xiao Xu Li^#, Jia Jun Hong^#, Yun Xia Wang#, Jian Bo Fu, Hong Yang, Chun Yan Yu, Feng Cheng Li, Jie Hu, Wei Wei Xue, Yu Yang Jiang, Yu Zong Chen*, Feng Zhu*. Clinical trials, progression-speed differentiating features, and swiftness rule of the innovative targets of first-in-class drugs.  Briefings in Bioinformatics (IF:8.990, 一区top). 21(2):649-662 (2020).

11. Ying Hong Li^#, Chun Yan Yu^#, Xiao Xu Li^#, Peng Zhang, Jing Tang, Qingxia Yang,Tingting Fu, Xiaoyu Zhang, Xuejiao Cui, Gao Tu, Yang Zhang, Shuang Li, Fengyuan Yang, Qiu Sun, Chu Qin, Xian Zeng, Zhe Chen, Yu Zong Chen*, Feng Zhu*. Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics. Nucleic Acids Research (IF:11.561, 一区 TOP). 46(D1): 1121-1127 (2018).

12. Ying Hong Li^#, Pan Pan Wang^#, Xiao Xu Li^#, Chun Yan Yu, Hong Yang, Jin Zhou, Wei Wei Xue, Jun Tan, Feng Zhu*. The human kinome targeted by FDA approved multi-target drugs and combination products: a comparative study from the drug-target interaction network perspective. PLoS ONE (IF:3.057, 三区). 11(11): e0165737 (2016).

13. Ying Hong Li^#, Jing Yu Xu^#, Lin Tao^#, Xiao Feng Li, Shuang Li, Xian Zeng, Shang Ying Chen, Peng Zhang, Chu Qin, Cheng Zhang, Zhe Chen, Feng Zhu*, Yu Zong Chen. SVM-Prot 2016: a web-server for machine learning prediction of protein functional families from sequence irrespective of similarity. PLoS ONE (IF:3.057 三区). 11(8): e0155290 (2016).

14. Hong Yang^#, Chu Qin^#, Ying Hong Li^#, Lin Tao, Jin Zhou, Chun Yan Yu, Feng Xu, Zhe Chen, Feng Zhu*, Yu Zong Chen*. Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information. Nucleic Acids Research (IF:9.202, 一区 TOP). 44(D1): 1069-1074 (2016).

硕士研究生招生计划：1-2人

招生专业：

        学硕：0710 生物学

        专硕：085400 电子信息

培养目标：

        1. 发现和解决生物信息学领域科学问题的能力

        2. 至少发表一篇SCI论文

        3. 具备读博所需的条件

招生要求：

        1. 具有python编程基础和英文论文读写能力

        2. 有机器学习和深度学习基础的学生优先

        3. 自驱力强，有干劲！

本科生科研训练招生计划：3-4人

培养目标：

        1. 发现和解决生物信息学领域技术问题的能力

        2. 参加至少一项全国赛事，争取获奖

        3. 争取发表一篇SCI论文

招生要求：

        1. 具有较强的python编程兴趣

        2. 具有一定的写作能力

        3. 自驱力强，有干劲！